Our Scientific Framework

Adult tobacco consumers are at the center of everything we do. From scientists to engineers and product developers to consumer researchers, we are accelerating investments in understanding their needs, moments and preferences, which in turn, enables us to develop innovative smoke-free products that reduce the harm caused by tobacco.
We follow a rigorous scientific framework for evaluating potentially reduced-risk tobacco products and supporting product applications to the Food and Drug Administration. This framework enables us to evaluate smoke-free products from product design to individual risk assessment to overall population impact.
Constituent
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THE PRODUCT
- Chemistry Manufacturing and Controls
- Product Stability
- Chemical characterization
Individual Risk
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EXPOSURE and HEALTH RISK
- Toxicology & Risk Assessment
- Health risk assessment (absolute and relative)
- Human Studies
- Human Factors Assessment
Population Harm
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IMPACT on the POPULATION
- Risk perceptions (absolute and relative)
- Impact of product on users
- Impact on non-users
- Overall impact on the population
- Environmental Assessment